Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels generate inward cation currents that contribute to rhythmic electrical activity in the heart and brain. [...]

Small conductance Ca²⁺-activated K⁺ (SK) channels are heteromeric complexes composed of pore-forming α subunits and constitutively associated calmodulin (CaM), which bind [...]

Acid-sensing ion channels (ASICs), initially thought to gate solely via proton binding, have been shown to activate through pH-independent mechanisms, revealing diverse r [...]

This dissertation investigates the relationship between structure and function of ATP‑sensitive potassium (KATP) channels in pancreatic cells. Mutations in KATP channel p [...]

Potassium channels regulate cell excitability by gating K⁺ flux through transmembrane pores. Inward rectifier (Kir) channels, including ATP-sensitive K⁺ (KATP) channels, [...]