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1.
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Purkinje cells are key regulators of motor coordination, and disruptions in their regular firing patterns contribute to cerebellar ataxias. This thesis examines how alter [...]
2010 |
Dissertation |
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2.
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3.
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4.
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My work resulted in the discovery of a novel KATP channel pharmacochaperone, Aekatperone, through AI-driven virtual screening of the drug binding site using the Cryo-EM s [...]
2025-01-29 |
Dissertation |
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5.
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Drosophila melanogaster contains a single small-conductance Ca²⁺‑activated K⁺ (SK) channel gene most closely related to mammalian SK1, a channel that has proven difficult [...]
2007 |
Dissertation |
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6.
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7.
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8.
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α2δ proteins (CACNA2D1-4) are auxiliary subunits to voltage-gated calcium channels (VGCCs), and they contribute to VGCC trafficking to the plasma membrane. However, there [...]
2021 |
Dissertation |
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9.
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Ca²⁺-activated small-conductance K⁺ (SK) channels regulate neuronal excitability by coupling intracellular Ca²⁺ signals to membrane hyperpolarization. Using electrophysio [...]
2006 |
Dissertation |
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10.
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ATP‑sensitive potassium (KATP) channels link cellular metabolism to electrical activity, a process essential for insulin secretion in pancreatic β‑cells. Dysfunction of K [...]
2010 |
Dissertation |
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