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Long-term potentiation (LTP) relies on coordinated kinase activity, including CaMKII and ERK, to regulate synaptic strength through AMPA receptor function and trafficking [...]
2006 | Dissertation |
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Copper homeostasis is essential for cellular function, requiring precise regulation to meet metabolic needs while preventing toxicity. ATP7B, a P‑type ATPase copper trans [...]
2008 | Dissertation |
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Glutamate, the primary excitatory neurotransmitter in the brain, must be rapidly cleared from the extracellular space to prevent excitotoxicity and maintain precise synap [...]
2009 | Dissertation |
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Actin crosslinkers help shape the structure and mechanics of hair cell stereocilia. We identified several abundant crosslinkers and examined the developmentally regulated [...]
2010 | Thesis |
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Soluble epoxide hydrolase (sEH) is a therapeutic target for cardiovascular diseases, including stroke. Current inhibitors act on the hydrolase catalytic site, but a human [...]
2013 | Dissertation |