Concern about safety and, likewise, errors in medicine exploded after the first Institute of Medicine report “To Err is Human: building a safer health system” in 1999. (1 [...]

Burkholderia pseudomallei, the causative agent of melioidosis, relies on iron acquisition for virulence, yet these systems remain poorly characterized beyond the malleoba [...]

The transcription factor Olig2 is essential for the specification of neurons and oligodendrocytes, as well as a subset of astrocytes during both neural tube and telencep [...]

The transcriptional co-repressor, Rcor1, is a critical component of gene expression regulatory machinery. It interacts with two important histone modification enzymes an [...]

Genome-wide studies depend heavily on the quality and consistency of integrated annotation data from diverse computational and experimental sources. This thesis presents [...]