We recorded light-evoked lateral inhibitory postsynaptic currents (L-IPSCs) from ON-type mixed rod/cone bipolar cell terminals in goldfish retina to characterize their ti [...]

The visual transduction system provides a model for GPCR signaling and inactivation, where rhodopsin activation is quenched through retinal release, photoproduct conversi [...]

Dopamine signaling depends on rapid removal of dopamine from the synapse by the dopamine transporter (DAT), making DAT regulation critical for normal neurotransmission an [...]

The dim-light photoreceptor rhodopsin has been a structural model for G protein-coupled receptors (GPCRs) for decades, so much so that the largest class of GPCRs is commo [...]

Recent research in children with Phenylketonuria (PKU), the most common inherited disorder of amino acid metabolism, suggests they have decreased bone mineral density (BM [...]

In some early work in which we were using a Vitamin A deficient diet, we experienced considerable difficulty which we attributed to variations in the Vitamin A factor i [...]

Nonhuman primate studies may help elucidate the role of vitamin D on glucose homeostasis because they provide a more physiologically related model and may eliminate some [...]