Marijuana legalization across the United States has led to an increase in medical and recreational use in adults. Furthermore, the prevalence of marijuana use in pregnant [...]

Lymphocytic choriomeningitis virus (LCMV) infection in mice provides a robust model for studying CD8⁺ T cell immunity. This dissertation demonstrates that vaccination wit [...]

It is well established that altered postsynaptic receptor activity leads to changes in presynaptic transmission and presynaptic connectivity throughout the nervous system [...]

Pioneer neurons establish the initial nervous system structure by extending axons toward distant targets, but their molecular distinction from follower neurons was previo [...]There are movie files (MP4s) associated with this document.

Pioneer neurons are the first to extend their axons into a target tissue during nervous system development. Pioneer axon tracts act as a scaffold for subsequent extension [...]

The melanocortin system regulates diverse physiological functions in vertebrates, with unique adaptations in teleosts. Using zebrafish, we characterized two agouti protei [...]

Hair cells (HCs) mediate auditory and vestibular sensation through synaptic transmission. Here, I identify asteroid (ast), an ENU-induced deafness mutant, as encoding ves [...]

Zebrafish serve as a key model for auditory and vestibular research. We developed a novel method to quantify vestibular defects in larvae using the vestibulo-ocular refle [...]

Hair cells transduce physical forces into electrical signals in nerves through a process called mechano-electrical transduction (MET), allowing auditory and vestibular [...]

This study examined the fasting response of Native Alaskan children homozygous for the CPT1A c.1436C→T variant, which reduces hepatic fatty acid oxidation. Five children [...]