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Despite decades of conventional chemotherapy, the prognosis for patients with acute myeloid leukemia (AML) remains dismal, with 75% of patients succumbing to their diseas [...]
2021 |
Article |
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The immune system is a double-edged sword -- too little immunity we become susceptible to infection; too overactive and it leads to autoimmune diseases. This study guide [...]
2020-09-29 |
Learning object |
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3.
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Tissue-resident memory (TRM) CD8+ T cells permanently reside within non-lymphoid tissues where they provide a first-line of defense against invading pathogens. How-ever, [...]
2020 |
Thesis |
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The ability of tumors to induce immunosuppression and inhibit the cytolytic function of tumor-infiltrating lymphocytes (TIL) is a major obstacle to creating effective imm [...]
2020 |
Dissertation |
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MR1-restricted T (MR1T) cells are part of a growing class of unconventional T cells that have emerged as important players in the early response to microbial infection. T [...]
2019 |
Dissertation |
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6.
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Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of malignancies, with a dismal survival rate and limited treatment options. Advances in therapeutic modalit [...]
2019 |
Dissertation |
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