Black and white photograph of Bruce Magun, Ph.D., Chair of Department of Cell and Developmental Biology.

Black and white photograph of Reid S. (Sam) Connell laughing with two colleagues as he receives or hands out a flower.

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Black and white photograph of Bruce Magun, Chair of the Department of Cell and Developmental Biology, writing at his desk.

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This novel computational framework for the analysis of single-cell gene expression data from human tumor samples enables the identification of molecular activity associat [...]

This dissertation provides a deep exploration of how mammary epithelial cells respond to microenvironmental signals. Through a progression of increasingly complex models [...]

Cancer is now the biggest single cause of mortality worldwide, incidence has increased by 11% in four years and cases are forecast to rise by 75% over the next 20 years. [...]

Cells in vivo are continuously exposed to a range of small messenger proteins (microenvironmental ligands). Microenvironmental ligands bind to cell-surface receptors and [...]

During development, cells must migrate from their origin to their final destination, a process that is dependent on the actin cytoskeleton. Cells can migrate independentl [...]

Allogeneic hematopoietic cell transplantation (allo HCT) is the only curative therapy for patients with intermediate-2 or high risk myelofibrosis (MF). We sought to exami [...]