Next-generation sequencing (NGS) technologies have provided opportunities for developing personalized treatments for patients. Given the rapid advances in technology and [...]

With the growing value of next generation sequencing (NGS) assays for the determination of minimal residual disease (MRD) in the clinic, the con?dent and sensitive detect [...]

Network-based approaches are widely used for analyzing large-scale genomic data and searching for disease driver genes. Diffusion-based approaches are one of the most p [...]

Public omics datasets from sequencing and array-based platforms now amount to millions of samples across thousands of studies and projects. This wealth of data is difficu [...]

This work reviews the technical, clinical and ethical complexities related to use of genomic data to provide clinical informaticists a framework to evaluate the utility a [...]

Prostate cancer is the second most commonly diagnosed cancer in men worldwide. This thesis leverages novel single-cell epigenomic and proteomic approaches to aid in the i [...]

Vocal learning is the ability to learn vocalizations through imitation, and is a rare trait shared by only a few lineages of mammals and three groups of birds. Songbirds [...]