1.
PGRP3 is a protein that helps the body recognize and respond to bacteria based on the essential structures of the bacteria. They are believed to act by helping to maintai [...]
2023-11-08 | Thesis |
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This dissertation uncovers how PARP7 regulates transcription and innate immune signaling, with a focus on its suppression of type I interferon (IFN-I) expression. It iden [...]
2025-09-19 | Dissertation |
4.
PARPs are a family of 17 proteins that regulate a diverse range of cellular processes through the transfer of ADP-ribose from NAD+ to amino acids on protein targets, a pr [...]
2021 | Dissertation |
5.
Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of malignancies, with a dismal survival rate and limited treatment options. Advances in therapeutic modalit [...]
2019 | Dissertation |
6.
ADP-ribosylation is a dynamic post-translational modification predominantly catalyzed by a large family of enzymes called PARPs. PARPs are implicated in diseases such as [...]
2025-03-14 | Dissertation |
7.
In the absence of a prophylactic vaccine and curative strategies, the daily use of antiretroviral therapy (ART) is essential for preventing and maintaining HIV infection. [...]
2022 | Dissertation |