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Interferon lambda is critical for host viral defense at mucosal surfaces and contributes unique immunomodulatory effects primarily in epithelial cells. Although expressed [...]
2021 |
Abstract |
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Interferon regulatory factor 6 plays a significant role in the regulation of intestinal epithelial cell identity, interferon response, and apoptosis.
2024-04-09 |
Thesis |
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Colorectal cancer (CRC) is the 3rd most prevalent cancer worldwide. In treating cancer, the tumor microenvironment has a large impact on cell behavior, growth, and tumor [...]
2024 |
Abstract |
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Acute myeloid leukemia (AML) is the most common leukemia in adults and is primarily diagnosed in older patients. The combination of the BCL2 inhibitor, venetoclax, with a [...]
2024 |
Abstract |
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Interferon (IFN) family cytokines stimulate a broad group of genes known as interferon stimulated gene (ISGs). The primary function of ISGs is to provide antiviral host d [...]
2022 |
Dissertation |
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