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The structural and functional characterization of the human bile acid ion channel in the presence and absence of calcium are discussed.
2025-01-10 | Dissertation |
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Extracellular ATP is a critical signaling molecule that is found in a wide range of concentrations across cellular environments. The family of nonselective cation channel [...]
2022 | Abstract |
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By leveraging the inhibitory effects of divalent cations Ca2+ and Ba2+, I determined the structure of a homotrimeric ASIC in a high pH resting conformation by both x-ray [...]
2019 | Dissertation |