Angiotensin converting enzyme 2 (ACE2) is a key regulator of the renin angiotensin system (RAS) that acts by degrading angiotensin II (AngII). Within the kidney, ACE2 is [...]

Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are un [...]

Cardiorenal syndrome type 1 (CRS1) is acute kidney injury (AKI) due to rapid worsening of cardiac function, and is a common cause of AKI. Ischemic AKI and subsequent chro [...]

Current risk-adjusted models used to predict donor heart utilization and cardiac graft survival from organ donors after brain death (DBDs) do not include donor critical c [...]

Destruction of skeletal muscle (rhabdomyolysis) releases myoglobin, causing rhabdomyolysis-induced acute renal injury (rhAKI). As rhAKI commonly occurs in austere environ [...]

Acute kidney injury (AKI) is a widespread health problem, with increased incidence among hospitalized patients. The most common cause of AKI is ischemic injury, which tar [...]