This dissertation develops noninvasive methods for inferring physiologic processes using features of otoacoustic emissions (OAEs). Studies demonstrate that stimulus‑frequ [...]

Hearing lose affects 360 million people worldwide and a largely preventable contributor is excessive noise. Exposure to loud noise damages the delicate hair cells of [...]

The cochlear nuclei are the first brain centers for auditory processing, where synaptic inhibition shapes neural output. Using patch-clamp recordings in avian and mammali [...]

This interview with Dr. Peter Barr-Gillespie explores his scientific and administrative career. Barr-Gillespie recounts his early interest in science, beginning with chem [...]

The overall focus of my doctoral research was to characterize how sensory and behavioral context affect how the auditory brain perceives and interprets sound.

Inner ear hair cells are critical for our senses of hearing and balance. Mechanotransduction happens in the hair bundle, a unique sub-cellular organelle of the hair cells [...]

Inner ear hair cells are essential for hearing, balance, and acceleration, yet they do not regenerate in humans, making their maintenance critical for preventing age-rela [...]

Hair cells transduce physical forces into electrical signals in nerves through a process called mechano-electrical transduction (MET), allowing auditory and vestibular [...]

Concatenative synthesis, the dominant Text-to-Speech (TTS) method, often produces audible discontinuities due to mismatched phonemic and prosodic contexts. Previous linea [...]

Sensory adaptation in inner ear hair cells depends on myosin‑1c (Myo1c), the molecular motor that regulates mechanotransduction channel sensitivity. This dissertation exa [...]