Immune checkpoint blockade (ICB) therapy targets checkpoint proteins to restore normal function to the immune system so that it can attack cancer cells. It is used succes [...]

Immune checkpoint inhibitor (ICI) therapies, such as anti-PD1 and anti-CTLA4, have proved to be clinically effective in numerous malignant diseases due to their ability t [...]

Uveal melanoma (UM) is a rare but aggressive disease, with >50% of tumors propagating metastatic disease spread - associated with nearly uniform fatality. Despite sign [...]