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Stevens.Kristen.2020
A reward system polygenic risk score for predicting obesity and substance addiction
Stevens, Kristen ; McWeeney, Shannon
Genome-wide polygenic risk scores (PRS) can now predict complex genetic disease risk with nearly the same ability as tests for monogenic diseases. Despite this, there is [...]
2020 | Dissertation |
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4076_etd
Strategies to improve predictions of outcome in glioblastoma multiforme and muscle-invasive bladder cancer
Claunch, Cheryl ; Gray, Joe W. ; Korkola, James E. ; Sears, Rosalie[...]
Advancing precision medicine in the treatment of cancer is complex and requires extensive molecular profiling to identify therapeutic targets and appropriately stratify p [...]
2018-07-01 | Dissertation |
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Toward improved prediction of bone marrow toxicity in Lu-177-DOTATATE therapy through exploration of patient risk factors, refined dosimetry meth[...]
Doyle, Colin ; Mench, Anna ; Winters, Celeste ; Wyatt, Cory[...]
This work aims to better characterize patients who do not complete treatment with Lu-177-DOTATATE in order to achieve more personalized medicine in the future. Three inve [...]
2026-05-12 | Thesis |
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Using in vitro models to predict TKI sensitivities of PDGFRA-mutant gastrointestinal stromal tumor
Khosroyani, Homma ; Heinrich, Michael
The majority of PDGFRA-mutant gastrointestinal stromal tumors (GIST) harbor exon 18 mutations, most commonly D842V, which is treated with avapritinib (a new type I TKI) b [...]
2025-09-19 | Dissertation |
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