The mutational status of platelet-receptor PEAR1 was recently identified as a major factor for survival of young patients with Acute Myeloid Leukemia. While studies show [...]

PARPs are a family of 17 proteins that regulate a diverse range of cellular processes through the transfer of ADP-ribose from NAD+ to amino acids on protein targets, a pr [...]

Tuberculosis (TB) is a devastating illness. In the search for novel anti-TB therapies, there is growing interest in host-directed therapy (HDT), which seeks to synergize [...]

The goal of this project is to document the bioinformatics tasks currently carried out by researchers in the fields of genomics and proteomics. This will help us identify [...]

The Portland Alcohol Research Center (PARC) was established to investigate the genetic basis of alcohol dependence. One line of inquiry utilizes mouse strains that are w [...]

Modern biological research is increasingly dependent on information technology. The Human Genome Project, together with increased computer availability, has catalyzed the [...]

Reliable identification of deamidation remains challenging when using low-resolution mass spectrometry due to the MS/MS mis-triggers on first isotopic p [...]

Successful cancer treatment continues to elude modern medicine and its arsenal of therapeutic strategies. Therapy resistance is driven by tumor heterogeneity, complex int [...]

Mass spectrometry has become a vital tool in the field of proteomics. This technique enables the study of proteins on a much larger scale, facilitating further biological [...]

HER2-positive breast cancer is an aggressive subtype of breast cancer with patients having significantly lower survival rates compared to other breast cancers. HER2-posit [...]