The overwhelming majority (~90%) of patients with pancreatic ductal adenocarcinoma (PDAC) will be treated with systemic standard-of-care chemotherapeutic regimens at some [...]

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor outcomes, partly due to dysfunctional vascularization and complex tumor-stromal interactions. Th [...]

Our lab recently identified radiation responsive microRNAs (miRNA) in colorectal cancer (CRC). The most upregulated candidate, miRNA 451a, inhibited tumor cell proliferat [...]

Rett syndrome is a neurological disease due to loss-of-function mutations in the transcription factor, Methyl CpG binding protein 2 (MECP2). Because overexpression of end [...]