Ira Pauly, M.D. describes in this interview his life and career in psychiatry and how he came to specialize in treatment of the transgender community. Raised in Beverly Hills, California, he went to UCLA Medical School in the 1950s. Pauly interned in surgery, but decided to try a residency at Cornell Medical Center in New York. It was during a consultation rotation in 1961 that he met his first transgender person. He tells how little literature there was on the subject at the time. He notes how the terminology has evolved over time. He wrote a paper about it, which was published in 1965. In 1962 he came to UOMS where group therapy was practiced. He stayed here until 1978, when he became Chair at University of Nevada Medical School until 1995. He taught abroad and ran an adult mental health clinic in Reno. He speaks of colleagues and his work with the transgender community.