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Abstract

Is the capacity of Mtb-specific CD4+ and CD8+ T cells to produce three key Th-1 cytokines compromised among Ugandan children with TB as compared to Ugandan adults with TB? Does use of novel Mtb-antigens (as compared to antigens utilized in commercial blood tests for Mtb-infection) identify additional Th-1 Mtb-specific T cells among Ugandan children with TB as compared to Ugandan adults with TB?

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