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Abstract

TRALI occurs when blood plasma contains granulocyte specific antibodies or human leukocyte antigens, which correspond to antigens found on donor white blood cells. Sudden pulmonary edema is caused by increased capillary permeability. Due to granulocyte enzyme release, TRALI is most associated with the administration of blood products that contain plasma, such as fresh frozen plasma. This project addresses the need for transfusion related to acute lung injury (TRALI) research data accessibility. Sufficient data analysis cannot be achieved with data stored in paper format through the use of a web data entry interface and relational database. However, rapid analysis will be possible.

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