Access through the computer, medical knowledge resources are increasingly being provided on the Internet. And, it is as through the user interface that the user communicates with the computer. As a result, human computer interactions associated with user interface assume a more significant role. Usability testing, a component of human factors engineering, is an important part of the software development lifecycle and addresses user design. This paper examines usability testing of Web resources in the healthcare setting. The method under study is known as Discount Usability Engineering (DUE), which incorporates accepted methods of usability testing but is applied using a relatively small sample of users and experts and employs heuristic evaluation, think aloud sessions and scenarios to provide results in the form of needed changes.