Cross-sector collaboration to increase active transportation: a grounded theory from the health sector perspective

Extinction is a complex period of learning during which a predicted relationship between stimuli (i.e. conditioned stimulus-unconditioned stimulus association) is inhibited by presentation of the predictive stimulus alone (i.e. non- reinforced conditioned stimulus), and this learning can be impaired by blockade of dopamine receptor activity. Thus, examining the relationship between dopamine and extinction may be beneficial to understanding basic features of learning and memory. Furthermore, enhancing extinction may be beneficial at a clinical level, as impaired extinction is hypothesized to contribute to a number of diseases of learning and memory, such as posttraumatic stress disorder and substance use disorders. The overarching goal of this dissertation is to examine the consequence of altering dopamine signaling during acquisition and extinction of fear and reward to specify the contribution of dopamine signaling within these particular phases of learning.