The CDC reports an estimated 20 million new sexually transmitted infections (STIs) occur annually, with the cost of treating these new STI cases estimated to be about 16 billion. With more than 50% affecting people between the ages of 15-24 years of age, and 15-24-year-old patients comprising only one-quarter of the US population, there is a disproportionate weight of STI cases affecting American youth. Although schools provide sexual health education, they cover the subject matter very broadly and with less focus; young people want practical guidance and help in avoiding STIs and pregnancies. All ethnic and racial groups are affected, but American Indian/Alaska Natives (AI/AN), as one of the smallest ethnic and racial groups in the United States, have experienced persistent disparities related to STI/HIV and teen pregnancies among their youth. The aim of this project includes a literature review of previous messaging studies to inform the design of text messages that could be used to recruit and consent study participants, promote condom use and appropriate STI testing, and evaluate the effectiveness of intervention.