Go to main content

Novel functions of USP36: regulation of histone 2B and the P53-MDM2 pathway through deubiquitination

DeVine, Tiffany
2015
Get Accessible Copy
Download
Add to Basket

Evading cellular programs that limit growth and proliferation is required for both tumor formation and maintenance. The work presented in this dissertation uncovers two novel mechanisms through which USP36, a key nucleolar deubiquitinating enzyme (DUB) implicated in ribosome biogenesis, regulates cell growth and proliferation.

Title
Novel functions of USP36: regulation of histone 2B and the P53-MDM2 pathway through deubiquitination
Creator
DeVine, Tiffany : Oregon Health and Science University
Contributor
Dai, Mu-Shui : Mentor : Oregon Health and Science University
Date
2015
Subjects
Keywords
DOI
https://doi.org/10.6083/M4PV6JB1
Content Type
Dissertation
Degree Type
Ph.D.
Department
Department of Cell, Developmental and Cancer Biology
School
School of Medicine
Copyright Status
Usage Statement
Record ID
2954
Record Created
2023-06-29
Disclaimer

These documents are archival records. They are retained for historical reference only.

Need an accessible version? Use the ‘Get Accessible Copy’ link above.

Record Appears in
Organizations > Departments and Divisions > School of Medicine Basic Sciences Departments > Department of Cell, Developmental and Cancer Biology
OHSU Works > Student Work > Degrees > Doctor of Philosophy (Ph.D.)
Organizations > Schools > School of Medicine
Theses and Dissertations
Featured Collections
Dissertations
All Records

Metric
From
To
Interval
Export
Download Full History