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Abstract
Work in this thesis characterizes the cellular phenotype of a novel progenitor-derived endothelial-like cell, two in vivo assessments of bioprosthetic venous valve endothelialization, the hemocompatibility consequences of crosslinking a decellularized matrix, and a novel modification of decellularized matrix for protein C activation. This dissertation describes novel biomaterials designed for vascular applications for the advancement of cardiovascular medicine.