The subjective effects of ethanol in Rhesus monkeys: characterizing the role of the nucleus accumbens using chemogenetics

Alcoholism is a chronic, progressive disorder often characterized by patterns of binge drinking that leads to detrimental health consequences and a great economic burden on society. Alcohol (ethanol) is known to produce interoceptive (i.e., internally generated) effects that can be recognized and described by the user. Thus, the first aim of this dissertation was to characterize the pharmacological basis of ethanol discrimination in rhesus macaques.