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Abstract

Cannabis is the most frequently used federally illicit substance in pregnancy. The available human literature suggests that infants exposed to cannabis in pregnancy display signs of impaired neurodevelopment, including altered visual perception, exaggerated response to stimuli, and a high-pitched cry. Results from human studies are often confounded and limited by retrospective observational data, thus a relevant, translational animal model is needed. The objective of this study is to define the impact of chronic contemporary THC exposure on infant sensorimotor development and socioemotional behavior in a rhesus macaque model.

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