Patients with obstructive hypertrophic cardiomyopathy (oHCM) frequently present with heart failure symptoms refractory to medical therapy and require septal myectomy (SM). The magnitude of benefit from SM is thought to be better than the recently reported data from EXPLORER-HCM and REDWOOD-HCM trials. We prospectively investigated the association between SM, patient-reported 12-item Kansas City Cardiomyopathy Questionnaire (KCCQ-12) and physician-reported NYHA class in a community-based cohort of oHCM. SM ± submitral valve repair is associated with improvement in NYHA class and KCCQ-12 but with a varying magnitude of benefit.
Details
Title
Improved NYHA class and KCCQ-12 after septal myectomy in patients with obstructive hypertrophic cardiomyopathy
Creator
Cambron, Claire : Oregon Health and Science University Lin, Lucy : Oregon Health and Science University Kim, Morris : Oregon Health and Science University Rashdan, Lana : Oregon Health and Science University Li, Sarah : Oregon Health and Science University Zhao, Yuanzi : Oregon Health and Science University Graham, Kellie : Oregon Health and Science University Fischer, Katherine : Oregon Health and Science University Nazer, Babak : Oregon Health and Science University Heitner, Stephen B. : Oregon Health and Science University Song, Howard : Oregon Health and Science University Masri, Ahmad : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2023
