Cancer cachexia is a co-morbidity highly prevalent in pancreatic ductal adenocarcinoma (PDAC) patients and results in a decreased quality of life.This work expands on prior knowledge of IL-6 in cancer cachexia, implicates impaired hepatic metabolism as an early event in cachexia progression, and highlights the liver as a target for potential interventions in cachexia treatment.
Details
Title
Inflammatory signaling in the liver drives early metabolic disruption in pancreatic cancer cachexia
Creator
Arneson-Wissink, Paige : Oregon Health and Science University Mendez, Heike : Oregon Health and Science University Pelz, Katherine : Oregon Health and Science University Dickie, Jessica : Oregon Health and Science University Marks, Daniel : Oregon Health and Science University Grossberg, Aaron : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2023
