To what extent does ChatGPT-4 generate accurate, meaningful, and quality alt-text for digital images in online nursing courses? The Accessibility Resource Center at OHSU includes alt-text images as one of the important steps for having accessible lectures and online content. However, it is often a tedious task for instructors and course designers to create accessible online courses in multiple formats. As an example, complicated imagery requires alternative text (alt-text) for various learner needs. Meanwhile, writing alt-text can be difficult and time-consuming, especially when the image is complex. Generative AI offers a solution for this because these tools can now describe imagery (including tables and graphs) in a matter of seconds.