In people with Parkinson's disease (PD), walking impairments like reduced stability, speed, and stride length are common. These impairments involve a shift from automatic to compensatory control, mainly in the prefrontal cortex (PFC). Increased gait variability, seen in PD, suggests reduced automaticity and higher PFC activity, indicating greater attentional demand. However, it's unclear if specific gait domains correlate with changes in PFC activity. We hypothesize that increased PFC activity during walking may correspond to higher gait variability.
Details
Title
Association between pre-frontal cortex activity and gait domains in people with Parkinson's disease
Creator
Ragothaman, Anjanibhargavi : Oregon Health and Science University Liu, William : Oregon Health and Science University Silva-Batista, Carla : Oregon Health and Science University Carlson-Kuhta, Patricia : Oregon Health and Science University Harker, Graham : Oregon Health and Science University Ellison, Jacqueline : Oregon Health and Science University Horak, Fay B. : Oregon Health and Science University Mancini, Martina : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2024