Here we evaluated the accuracy of several freely available software packages to correct for variable gene copy numbers in microbiome profiling using the 16S rRNA gene. We then applied these corrections to a published urinary microbiome dataset to show that the use of one of these packages has a measurable effect on the final results of human urinary microbiome studies.
Title
Evaluation of currently available 16S rRNA gene copy number correction software packages for accuracy and impact in a mock microbial community and urinary microbiome dataset
Creator
Shah, Rebecca : Oregon Health and Science University
Karstens, Lisa : Oregon Health and Science University
Publisher
Oregon Health and Science University
Date
2024-06-21
Language
English
Content Type
Capstone
Degree Type
M.S.
Academic Program
Bioinformatics & Computational Biomedicine
Department
Department of Medical Informatics and Clinical Epidemiology
School
School of Medicine
Record ID
43710
Record Created
2024-09-19
