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Impacts of mesenchymal KITL/SCF in pancreatic tissue homeostasis and pancreatic ductal adenocarcinoma

Oñate, Maria Kathrina; Oon, Chet; Bhattacharyya, Sohinee; Low, Vivien; Chen, Canping; Zhao, Xiaofan; Arnold, Frank; Yan, Ziqiao; Pramod, Sneha; Hang, Yan; Ho, Yu-Jui
2025
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Abstract

A dissertation discussing the role of mesenchymal kit ligand (kitl) in the pancreas, specifically in regards to healthy tissue homeostasis, tissue architecture, and disease states pancreatitis and pancreatic ductal adenocarcinoma.

Details

Title
Impacts of mesenchymal KITL/SCF in pancreatic tissue homeostasis and pancreatic ductal adenocarcinoma
Creator
Oñate, Maria Kathrina : Oregon Health and Science University : (0000-0003-3495-6038)
Oon, Chet : Memorial Sloan Kettering Cancer Center : (0000-0002-1494-6628)
Bhattacharyya, Sohinee : Memorial Sloan Kettering Cancer Center : (0000-0001-6180-8415)
Low, Vivien : Memorial Sloan Kettering Cancer Center : (0000-0002-5284-9650)
Chen, Canping : Oregon Health and Science University : (0000-0003-4021-8592)
Zhao, Xiaofan : Oregon Health and Science University : (0000-0003-3364-8324)
Arnold, Frank : Memorial Sloan Kettering Cancer Center : (0000-0003-0025-3668)
Yan, Ziqiao : Stanford University : (0009-0001-6195-0849)
Pramod, Sneha : Memorial Sloan Kettering Cancer Center : (0000-0002-9282-3332)
Hang, Yan : Stanford University : (0000-0002-5166-2480)
Ho, Yu-Jui : Memorial Sloan Kettering Cancer Center : (0000-0002-7540-024X)
Contributor
Lowe, Scott PI (Memorial Sloan Kettering Cancer Center)
Kim, Seung PI (Stanford University)
Xia, Zheng PI (Oregon Health and Science University)
Sherman, Mara Mentor (Memorial Sloan Kettering Cancer Center)
Publisher
Oregon Health and Science University
Date
2025-03-21
Subjects
Keywords
DOI
https://doi.org/10.6083/bpxhc44333
Language
English
Related Resource
Has part: https://doi.org/10.1158/2159-8290.CD-24-1079
Related work citations
M. Kathrina. Oñate, Chet Oon, Sohinee Bhattacharyya, Vivien Low, Canping Chen, Xiaofan Zhao, Frank Arnold, Ziqiao Yan, Sneha Pramod, Yan Hang, Yu-Jui Ho, Scott W. Lowe, Seung K. Kim, Zheng Xia, Mara H. Sherman; Stromal KITL/SCF maintains pancreas tissue homeostasis and restrains tumor progression. Cancer Discov 2025; https://doi.org/10.1158/2159-8290.CD-24-1079
Content Type
Dissertation
Degree Type
Ph.D.
Academic Program
Cancer Biology (sunsetting)
Department
Department of Cell, Developmental and Cancer Biology
School
School of Medicine
Copyright Status
In copyright - joint owners
Usage Statement
Record ID
44333
Record Created
2025-03-17
Record Appears in
Organizations > Departments and Divisions > School of Medicine Basic Sciences Departments > Department of Cell, Developmental and Cancer Biology
OHSU Works > Student Work > Academic Programs > School of Medicine Programs > Cancer Biology (sunsetted)
OHSU Works > Student Work > Degrees > Doctor of Philosophy (Ph.D.)
Organizations > Schools > School of Medicine
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