Proactive mentorship and professional development are fundamental to the success of early career faculty. The Early Career Advancement Program (ECAP) within the OHSU School of Medicine (SOM) is designed to facilitate and optimize faculty productivity, promotion, and career satisfaction. ECAP originated within the Department of Cell, Developmental and Cancer Biology in 2014, and is currently in its fifth year of being broadly available to all new investigators within the SOM. Overseen by mid-career and senior OHSU scientists, ECAP delivers up to seven interactive workshops annually, facilitated by guest speakers from within the OHSU research community and external experts. These workshops are specifically designed to provide participants with practical experience and real-time feedback. Since its inception, ECAP has served over 150 OHSU faculty across 30 OHSU departments. Of the initial cohort (2015-2016) of faculty who joined ECAP as newly recruited SoM early career faculty, all have gone on to successfully compete for their first NIH R01 awards, and to advance to Associate Professor.