An expanding elderly population worldwide, with associated needs for medication and adherence assistance, requires an improved understanding of elders’ general medication management practices and preferences regarding medication reminder devices. The purpose of this study was to investigate elders’ preferences regarding a variety of commercially available medication reminder device types and reminding modes. The study also explored elders’ general medication management behavior. Findings suggest that elders’ medication reminder device preferences can be assessed via consideration of four general types of internal and external contextual factors: affective, cognitive, physical, and social factors. Preliminary study findings and design implications are discussed, along with plans for future analysis and research.