Clinicians have numerous and diverse information needs, and face a similarly diverse variety of obstacles preventing those needs from being met. Some of these obstacles are technical in nature, while others are organizational or educational. For many of the world’s clinicians, however, one of the most important obstacles is linguistic: the vast majority of internationally-published medical and scientific literature is written in the English language, which means that many potential users of this content are unable to do so without expending the significant additional time and effort required to read a foreign language. This dissertation describes a novel bilingual search interface that uses machine translation to present English-language MEDLINE search results in Spanish, along with an evaluation protocol that seeks to assess the effects of such an interface on subjects’ ability to identify relevant search results.