Secondary analyses of dietary data from PRISM clinical trials to evaluate safety and efficacy of pegvaliase for adults with PKU
Khoo, Vi V.
2019

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Abstract

Phenylketonuria (PKU) is a genetic disorder caused by a deficiency of phenylalanine hydroxylase leading to decreased conversion of phenylalanine (Phe) to tyrosine (Tyr). Pegvaliase™ (Palynziq™, BioMarin Pharmaceutical Inc., Novato, CA, USA), an injectable enzyme replacement therapy decreases plasma Phe by converting Phe intro trans-cinnamic acid and ammonia. This study aims to evaluate the changes in the dietary composition of participants with PKU on pegvaliase.

Details

Title Secondary analyses of dietary data from PRISM clinical trials to evaluate safety and efficacy of pegvaliase for adults with PKU
Creator Khoo, Vi V.
Publisher Oregon Health and Science University
Date 2019
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DOI https://doi.org/10.6083/9w0323552
Content Type Thesis
Degree Type M.S.
School School of Medicine
Record ID 7588
Record Created 2023-06-29
Record Appears in OHSU Works > Student Work > Degrees > Master of Science (M.S.)
Organizations > Schools > School of Medicine
OHSU Works > Student Work > Theses
Theses and Dissertations
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