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Abstract

Vitamin D has been shown to influence the coagulation cascade and may reduce the risk of thromboembolic events (TE), a leading cause of morbidity and mortality in the United States. This study examined the association between serum vitamin D levels, vitamin D intake, and a predicted long‑term vitamin D score with TE using data from NHANES III. Logistic regression models demonstrated that higher vitamin D status was generally associated with reduced odds of TE after adjustment for confounders. Lower vitamin D levels were linked to poorer outcomes, and serum vitamin D differed significantly across clinical risk groups. These findings support an inverse association between vitamin D status and thromboembolic risk and suggest potential public health implications for maintaining adequate vitamin D levels.

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