In Lao PDR, 33.5% of children under five years of age are stunted, 26% are underweight and 8% are severely wasted. Nutritional rehabilitation of malnourished children often requires dietary energy and protein supplementation. Water buffalo (WB), native to Southeast Asia, produce milk with higher energy and protein concentrations than dairy cattle (DC). Whey, a byproduct of cheese production and a source of protein and energy, is currently discarded in Lao PDR after making cheese. Energy and macronutrient concentrations of WB milk and liquid/dried whey were analyzed and compared to DC milk and whey data to determine suitability as a locally-sourced nutritional supplement.