There is a shortage of in-vitro model systems that mimic the dentin-pulp interface while enabling a real-time evaluation of dental pulp cells, dentin and biomaterials. Here, we optimized an organ-on-a-chip model system, the "Tooth-on-a-chip" and tested different biomaterials in real-time. Moreover, we developed a model of secondary caries on-chip co-culturing oral microcosm with dental pulp cells.
Details
Title
The tooth on-a-chip as model of dental pulp cell response to biomaterials and oral biolfim
Creator
França, Cristiane M. : Oregon Health and Science University Tahayeri, Anthony : Oregon Health and Science University Mansoorifar, Amin : Oregon Health and Science University Rodrigues, Nara : Oregon Health and Science University Cunha, Diana : Oregon Health and Science University Ferracane, Jack : Oregon Health and Science University Kreth, Jens : Oregon Health and Science University Bertassoni, Luiz E. : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2020
