Administration of chemotherapy via intra-arterial (IA) route results in a higher concentration of targeted chemotherapy against resilient brain malignancies with a decreased systemic chemotherapy side effect. Osmotic blood-brain barrier disruption (BBBD) further intensify drug delivery and effects on brain malignancies. The aim of this study is to determine the safety of the use of intra-arterial chemotherapy and blood brain barrier disruption to treat malignant brain tumors.
Details
Title
Safety of intra-arterial (IA) chemotherapy and blood brain barrier disruption (BBBD) for treatment of patients with malignant brain tumors
Creator
Tabb, John : Oregon Health and Science University Ambady, Prakash : Oregon Health and Science University Neuwelt, Edward : Oregon Health and Science University Uluc, Kutluay : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2022