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There has been a growth of interest in the application of quantum computation and quantum simulation to the many intractable computational problems in the biological sciences. While theoretical results imply the value of quantum information processing (QIP) to many of the challenging problems resident in this research domain, such as molecular dynamics simulation, oncogenic mutational signature inference, and phylogenetic tree inference, a framework to guide the realization of quantum proof of principle applications has yet to be clarified.

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