Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully characterized. This research utilizes a network-based approach to characterize coordinated alternative splicing variation and identify potential splicing event signatures of drug response in AML.
Details
Title
Transcriptome-wide characterization of alternative splicing variants in drug resistant AML
Creator
Egger, Julian : Oregon Health and Science University Zheng, Christina : Oregon Health and Science University McWeeney, Shannon : Oregon Health and Science University Wu, Guanming : Oregon Health and Science University Laderas, Ted : Oregon Health and Science University Hitzemann, Robert : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2020