Tauopathy and a-synucleinopathy often occur together in human brain diseases but most commonly in the context of B-amyloidosis. Tauopathy induced by a-synucleinopathy in the absence of B-amyloid has been demonstrated in vitro and in cultured cells but compelling examples of this in human disease are rare and limited largely to instances of familial Parkinson's disease due to mutations in the a-synuclein gene.
Details
Title
Survey of tauopathy in mitochondrial protein associated neurodegeneration
Creator
Nguyen, Vy : Oregon Health and Science University Garcia, Daphne : Oregon Health and Science University Setthavongsack, Naly : Oregon Health and Science University Shirley, Kristen : Oregon Health and Science University Krajbich, Victoria : Oregon Health and Science University Clark, David : Oregon Health and Science University Zhen, Dolly : Oregon Health and Science University Wakeman, Katrina : Oregon Health and Science University Jeong, Suh Y. : Oregon Health and Science University Van der Weijden, Marlous : Oregon Health and Science University Gregory, Allison : Oregon Health and Science University Hogarth, Penny : Oregon Health and Science University Hayflick, Susan : Oregon Health and Science University Woltjer, Randall : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2020