I have developed a co-mutation frequency network to infer functional redundancy between pairs of cancer genes. This analysis builds on previous work that leverages mutual exclusivity, or low co-mutation frequency, as a way to investigate the genetic mechanisms of tumorigenesis.
Details
Title
Inference of functional redundancy in cancer genes via a co-mutation frequency network
Creator
Klocke, Christopher : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2020