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Abstract

Alzheimer s Disease (AD) is the leading cause of dementia in the United States yet the genetics behind this complex disease remains unclear. With the exception of Apolipoprotein E e4 (APOE-e4), more than 40 loci have been implicated as common genetic risk factors of AD but none of these have been confirmed. We completed a genome-wide association study on 567 unrelated participants in the Alzheimer's Disease Neuroimaging Initiative ADNI data set.

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