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Abstract

Type II diabetes mellitus (T2DM) is a prevalent chronic disease affecting 90–95% of individuals with diabetes in the U.S. and is associated with severe complications and high healthcare costs. Depression frequently co-occurs with T2DM, worsening outcomes, increasing mortality, and often remaining undetected. While the causal relationship between T2DM and depression is unclear—potentially biochemical, physiological, or psychosocial—evidence supports a bidirectional link. Screening and treatment of depression in T2DM patients can improve health outcomes. Rising prevalence, including an 82% increase in Oregon since 1994, underscores the need for integrated strategies addressing both conditions.

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