As a part of the Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) precision medicine cancer trial, serial biopsies from cancer patients are collected and analyzed to inform treatment and advance the understanding of metastatic cancer. As of now, manual segmentation is a major time limiting factor in EM image analysis for cancer tissue. In order to combat this, there are projects underway to develop machine learning algorithms to automate segmentation. Automation will hopefully allow electron microscope analysis to be a new and informative avenue for cancer research.
Details
Title
Taking a closer look: imaging tumor microenvironments with 3D FIB-SEM reveals complex cellular interactions
Creator
Bueno, Cecilia : Oregon Health and Science University Riesterer, Jessica : Oregon Health and Science University Smith, Hannah : Oregon Health and Science University Machireddy, Archana : Oregon Health and Science University Stempinski, Erin : Oregon Health and Science University Loftis, Kevin : Oregon Health and Science University Stoltz, Kevin : Oregon Health and Science University Gray, Joe : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2021