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Abstract

PD is a neurodegenerative disorder characterized by motor dysfunction. Functional MRI offers a unique opportunity to non-invasively characterize brain function. In this study, we hypothesized that the motor functions observed in PD may involve connectivity in higher-level attention networks. Understanding the resting state functional networks that correlate with the severity of the motor symptoms would be valuable to understand the disease physiology. The objective of this study is to investigate the functional connectivity network pairs associated with the motor symptoms in people with Parkinson's disease (pwPD).

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